Paul de Kruif

Paul Henry de Kruif was an American microbiologist and writer. 

Publishing as Paul de Kruif, he is known for his 1926 book, Microbe Hunters. 

De Kruif was born March 2, 1890, in Zeeland, Michigan. In 1912, he graduated from the University of Michigan with a bachelor's degree, and he remained there to obtain a Ph.D., which was granted in 1916. He immediately entered service as a private in Mexico on the Pancho Villa Expedition and afterwards served as a lieutenant and a captain in World War I in France. Because of his service in the Sanitary Corps, he had occasional contacts with leading French biologists of the period.

After returning to the University of Michigan as an assistant professor, De Kruif briefly worked for the Rockefeller Institute (for Medical Research). He then became a full-time writer.

De Kruif assisted Sinclair Lewis with his Pulitzer Prize-winning novel Arrowsmith (1925) by providing the scientific and medical information required by the plot, along with character sketches. Even though Lewis was listed as the sole author, De Kruif's contribution was significant, and he received 25 percent of the royalties. Many believe the characters in the novel represent people known to De Kruif, with Martin Arrowsmith (a physician, unlike de Kruif) possibly representing himself.

While working for the Rockefeller Institute, De Kruif submitted an anonymous entry about modern medicine, for a book entitled Civilization. In the article, he decried the state of contemporary medical practice, which, because it lacked scientifically sound practices, he called "medical Ga-Ga-ism". De Kruif decried doctors as providing only a "mélange of religious ritual, more or less accurate folk-lore, and commercial cunning". When it was discovered that De Kruif was the author of the essay, he was fired from the Rockefeller Institute.

De Kruif was a staff writer for the Ladies' Home Journal, Country Gentleman, and Reader's Digest, contributing articles on science and medicine. He also served on commissions to promote research into infantile paralysis (polio).

De Kruif's book "Hunger Fighters" (1928) featured the story of Joseph Goldberger's experiments with inducing pellagra in convicts in a US prison (proving that the disease was caused by improper diet and not any kind of microbe); this chapter of the de Kruif book was, ironically, later cited by Nazi scientists as one of the inspirations for their own proposal to use convicts for their infamous medical experiments.

The Sweeping Wind, his autobiography was De Kruif's last book.

De Kruif died February 28, 1971, in Holland, Michigan.